Start by rimming the edges of your glasses with either salt or sugar. Dip the glass rims into simple syrup first, then into the sugar or salt. Set them aside for now.
Fill each glass about ¾ full with ice. This keeps your margarita nice and cold.
In a cocktail shaker, combine the tequila, blackberry liqueur, pineapple liqueur, Grand Marnier, sweet and sour mix, and blackberry syrup. Shake it up vigorously until everything is well mixed.
Pour the cocktail mixture into the ice-filled glasses. Garnish with a few fresh blackberries and a lime wheel for that extra touch of flair.