To start, season and boil the water for your pasta. Add the penne to the boiling water and cook according to directions on the box.
While the pasta is cooking, brown the Italian sausage. You can use mild or hot sausage, depending on your preference!
Drain the excess fat from the Italian sausage. Then, add your pasta sauce. I used premade pasta sauce but you can make your own meat sauce if you’d like! For premade sauce, use whatever is your favorite brand.
In a casserole baking dish, add your pasta and meat sauce. Mix together until well-combined. Season with Italian seasoning.
Mix in pepperoni and shredded cheese. I used Italian cheese, but you can use whatever your favorite pizza cheese is (mozzarella, pepper jack, etc.),
Top the pizza casserole with a layer of Italian cheese (my mixture is mozzarella, provolone, asiago, parmesan, and white cheddar).
Top with your favorite pizza toppings! I used pepperoni, green bell peppers, onions, black olives, and mushrooms.
Bake the pizza casserole at 350 for 30-35 minutes.
Serve & enjoy!